I know F2P isn't the "next" thing since it is already in use with some high profile games. But I expect that we will see a lot more companies going that direction in the next 5 years.
Living worlds are the logical progression for online games. If you can build a hugely interactive world and give players the proper social interaction tools, you've created a platform with long-lasting potential. I never thought that my father would get into online games as a 60-something retiree, yet he's sunk over 2,000 hours into Guild Wars to date. The more we evolve the MMO genre, the more we grow the audience.
As much as some folks like to snicker at motion and gesture control, I believe for certain gaming experiences these types of input will continue to evolve whether they are camera, touch screen, or gyroscopic in design. We've known for years that using a mouse for PC gaming had lots of possibilities, and developers continue to experiment with new approaches to user interaction. If a particular input feels natural for a given experience, it's worth trying on the platform that makes the most sense in ways that don't feel forced.
I also think the the shuffling that has occurred in the industry over the past ten years has also managed to produce the best generation of games we've ever seen. I can list a handful of classics for each and every platform for the last twenty years, but when you look at this era of consoles, there are at least thirty games deserving of a 90%+ review grade. We've also seen entire franchises develop over the course of a single generation, so that when you look at Call of Duty 2, it's amazing to think that Black Ops is still essentially a same-platform sequel. Despite my previous comments about publishers not risking too much, and going for polish over innovation, it largely only applies to third-party developers. The giants of Sony, Microsoft and Nintendo have been admirably bold in pursuing novel input devices and software, and I believe the games industry has never been in better shape.