The throwing knives off Deus Ex. I mean, you only ever got like 15 in the entire bloody game if you scoured every square inch with a fine tooth comb, but copping an MJ12 guard in the head with one of those babies was incredibly satisfying.

Oh, and never forgeting the concrete donkey.

Seriously? No one's mentioned the Yoshitsuna from Disgaea? It's stupidly powerful.
Other favorites include the hammer from Smash Bros. and banana bombs and holy hand grenades from Worms.

- Monkey Island's insult fights!

- ION CANNON!

- Portal Gun.

- Proximity mines... Just fill a GE level and BOOM!

- UaW's Peacebringer's pulse cannon's.

- Holy handgranade.

- (Golden) Banana bomb. ^^

- Yahtzee's hat.

The knife in pretty much any game. Take CoD4, the best players get tons of kills by just sprinting up to some moron and stabbing them.

the secret sowrd in your arm in assassin's creed

Tis sad that three pages has passed, and the Spinfusor aka Stormhammer aka Disklauncher has not been mentioned.

Their are other great weapons, but have all been mentioned, however, this is the one that is fondly remembered and loved by Tribers and ex-Tribers all over the world. Will be interesting to see how the spiritual successor of the series, Legions, incorporates this great and important weapon in Video Game history.

Mid Air > Head Shot

MA the McFukin

Dark Gravity gun from half life 2. best weapon ever. you can pick up and throw anything you want to a certain limit.

I like the sheep in Worms. The most amusing weapon ever.

Also the flak gun in UT was an amazingly versatile weapon.

I must agree with the satisfaction gained from wielding the double-barrelled shotgun in DOOM 2. That sound was amazing.

vanshi i don't know what it is but one of my friends told me to put it

Does the Crysis Nano-suit count?

*Maximum Strength*..."thump!"

Harman Smiths sniper rifle from the underatted Killer 7, just for the sheer power and preparation you have to go through when you use it

I'd love to try out the Portal Gun in a normal FPS match. So easy, just shoot the ceiling somewhere high on the map, then go around shooting people's feet. Or, if there's no falling damage, you can make your own murder holes in the ceilings.

And there's something about using a rusty circular sawblade to cut a zombie in half with the gravity gun that's very satisfying.

Concrete donkey from Worms 2

The bouncy-bullet sniper rifle from Jak 3. That weapon was easily my favourite - it lasted me the whole game.

Mine would have to be the Yamato from Phantasy Star Online. At least I think it was the Yamato. It's whichever weapon is a pair of blue greenish flat swords that can turn things to ice. I wouldn't mind own a pair of those. Most of the first person shooter weapon would simply get the FBI knocking on my door way too quickly.
For example, if I owned the Redeemer from Unreal Tournament. There's no way I could resist the urge to test it out in some capacity, and unless the great zombie apocalypse occurs around the same time I get the redeemer, odds are, I wouldn't get to hold onto it for very long.
With the Yamato. I'm pretty sure I could restrain myself from injuring anyone other than possibly myself (accidentally of course).

All time favorite was from Oddworld: Abe's Exoddus and I think Oddyssey, too, where Abe used the power of his mind to posses his enemies and ultimately made their heads explode. Too cool.
If I could do that I couldn't be trusted not to make the population of petty bureaucrats much smaller.

Exploding sheep!
Original game, of course - none of this worms2 nonsense...

People have mentioned the laptop and farsight guns in perfect dark - but it was all about Facility level + Proximity mines and PP7 only in Goldeneye. That has never got boring.

Also, the giant purple dildo from GTA: San Andreas. Brings cop whuppin' to a whole new level.

Oh, and, of course - if not the bile demon's projectile fart - then posessing a level 10 horned reaper and whizzing around with that scythe was always hilarious.

The Legendary Gitaroo from Gitaroo Man (of course). Saving the universe with music. Banzai motherfuckers.

The grav./energy hammer in Halo 3 is awesome, but it doesnt last long enough. Also loved the golf clubs, police batons and other "melee wepoans" from the gta series, kinda useless in the long run but they are all kinds of goodness when it comes to working out your frustrations.

Either the Portal device or the plasmids from BioShock. There's nothing more amusing than seeing a Big Daddy stumbling around swatting at a swarm of angry bees.

Cars-Crackdown
One of the few games in which you TRULY feel like an unstoppable badass.

The hidden blade from Assassin's Creed
Halo 3's Gravity Hammer
Burnout cars
Gravity Gun Redux from Half-Life 2
The Darkness
Minions from Overlord

Y'know... The Katana from Conker's Bad Fur Day was like the Masamune on crack... Them's a fun toy. And that gun from Perfect Dark with the X-Ray scope that shoots thru walls.

Remote mines from Goldeneye007...those were the days.

Ive got a few:
Someone mentioned the laser rifle from Xcom 1. I have to disagree because the laser pistol was a much better weapon. It worked WONDERFULLY with the rocket launcher in that you could easily stick it in your belt and whip it out whenever one of those dastardly aliens got too close. It also didn't get any accuracy penalties when fired with one hand, and could get more shots off in a round than the laser rifle. (that said, the laser rifle would be my second choice from that game)

The Shrinker from Duke3D has already gotten allot of love here so I wont describe it further.

Bullgut rocket launcher, Shogo:MAD - This gun is so ridiculously powerful and fun to shoot, I would consider going through the game using nothing but. Shogo was also the first game I ever played that featured full 3d explosions that weren't embarrassingly bad (Im looking at YOU Quake 2). This, combined with excellent sound effects and that undefinable 'feel' of a great gun makes willing to forgive that game's other faults.

BFG9000, Quake 2 version - The real joy of this weapon is actually born from it's handicap: its HUGE windup time. The thing makes a loud electronic noise and emits an alarming amount of scary green light for about 3 seconds before spitting a huge slow-moving green fireball. The thing that makes it special is the 'OH SHIT' reaction you get from people being shot at with it. If it just went off immediately, it wouldn't be anywhere near as much fun. The fact that it absolutely pastes people who use the 'wiggle dodge' form of evasion makes it all the more endearing to me.

If it absolutely, positively, has to erupt in flames...

Don't wait, INCINERATE!

Bioshock's plasmids are lots of fun. I played it so much that I memorized the different hand-signal things for each plasmid... yes, I have lots of time on my hands.

Spleenbag:
I played it so much that I memorized the different hand-signal things for each plasmid... yes, I have lots of time on my hands.

Ugh. Bad pun.

Mortal Kombat- Kabal's Hookswords.

Manhunt- The Crowbar.

Condemned: Criminal Origins- The Conduit. Hang on, I meant to say the Gas Pipe. No wait; I'm changing my answer again! The Paper Cutter Blade! No, the Sledgehammer! Er, the Fire Axe!!! Can I start again?

Defiantly the crowbar.
No questions asked.

Condemned:Criminal Origins. The flaming 2x4. Its a torch, its a club, its a tool of many uses

Sam Fisher's knife, got me out of many a hairy moment.

Oh... Mirabelle in Jade Empire. It's fun to use a huge gun in a kung fu battle.

Easily the ball from Little Big Adventure.

Dragon tooth sword from Deus Ex.

It's like a light saber with attitude.

Ah, a lot of those mentions bring back memories.. as for a favorite.. well, theres too many to mention. Any close-combat weapon for me, I get some perverse pleasure from sneaking up behind people and knifing/clubbing/batting/punching them right in the funsack.