Most quotes from Simon the sorcerer 1 + 2.
Simon: whats the pound of flesh loan?
Sectary: Thats our most basic loan. We'll lend you 2000 pieces of gold, and if you don't pay us it back, we can take a pound of flesh including blood and internal organs, from your body.

Colton Caramihalis:
The cake is a lie...
The cake is a lie...
The cake is a lie...
The cake is a lie...

i am very close to killing the next person who says that line it was only slightly funny in the game and it is now completly done to death.

any way here is my game quote

"SHOOT!SHOOT! YOU WANKERS!"
cod4 and a line from company of heroes

I'm surprised that, with all the quotes from Portal that came up, no one has mentioned this:
"Didn't we have some fun though? Remember when the platform was sliding into the fire pit and I said 'Goodbye' and you were like 'NO WAY!' and then I was all 'We pretended we were going to murder you'? That was great!"
Both the quote and the in-game delivery are fantastic.

"How appropriate, you fight like a cow."
"That's the second biggest monkey head I've ever seen!"
"OH BOY!!! It's a T-Shirt! Not my size but a nice one nonetheless!"
"It belongs in a museum!"

Monkey Island: still the funniest game ever made.

All of these are worth a read.

Metal Gear solid.

"Snake, we are not tools of the government or anyone else. Fighting was the only thing, the ONLY thing I was good at, but at least I fought for what I believed in. good by Snake."- Frank Yeager- Metal Gear Solid 1.

"Solidus Snake: Jack, listen to me. We're all born with an expiration date. No one lasts forever. Life is nothing but a grace period - for turning our genetic material into the next generation. The data of life is transferred from parent to child. That's how it works. But we have no heirs, no legacy. Cloned from our father, with the ability to reproduce conveniently engineered out. What is our legacy if we cannot pass the torch? Proof of our existence - a mark of some sort. When the torch is passed on from parent to child... it extends beyond DNA; information is imparted as well. All I want is to be remembered. By other people, by history."

"Solid Snake: We've inherited freedom from all those who have fought for it."

"The Boss: In 1960 I saw a vision of the ideal future from space. Three years earlier the Soviet Union had succeeded in launching Sputnik, the first manmade satellite in history, into orbit. This came as a huge shock to the United States. In response, America threw everything it had into its own manned space flight project, the Mercury project. Even as the Soviets seemed poised to send their first man into space America was still experimenting with chimpanzees in rockets. The government wanted human data. So they secretly decided to send a human being into space. I was the one they chose. At the time they didn't have the technology to block out cosmic rays and whoever they sent up would inevitably be exposed to heavy radiation. That's why they chose me. After all, I had already been irradiated once. Of course, you won't find any of this in the history books. I could see the planet as it appeared form space. That's when it finally hit me. Space exploration is nothing but another game in the power struggle between the US and USSR. Politics, economics, the arms race - they're all just arenas for meaningless competition. I'm sure you can see that. But the Earth itself has no boundaries. No East, No West, No Cold War. And the irony of it is, the United States and the Soviet Union are spending billions on their space programs and the missile race only to arrive at the same conclusion. In the 21st century everyone will be able to see that we are all just inhabitants of a little celestial body called Earth. A world without communism and capitalism... that is the world I wanted to see. But reality continued to betray me."

"Sigint: Well, let me tell you about the absolute worst, most sickening nightmare I ever had. This one isn't for the kids. OK, so there's this huge pile of crap, right? It's shaped like a giant tank, and it's walking around on two legs, goin' on a rampage and stompin' on people and houses and stuff. And this giant turd is carrying the nastiest missiles you ever saw. Like whenever it launches one of it's turd missiles... whatever it hits - people, trees, buildings - turns into sh**. My hometown, my old school, my family, my girlfriend, old man John... Everything in that turd's path turned into shit."

"The Sorrow: This world is one of sadness. Battle brings death. Death brings sorrow. The living may not hear them. Their voices may fall upon deaf ears. But make no mistake - the dead... are not silent. "

Cod 4
"Oh no, my tin-foil hat has come loose, I have lost connection to the mothership." MacMillan- COD4 (hidden sound files)

Max Payne

"The past is a gaping hole. You try to run from it, but the more you run, the deeper, more terrible it grows behind you, its edges yawning at your heels. Your only chance is to turn around and face it. But it's like looking down into the grave of your love, or kissing the mouth of a gun, a bullet trembling in its dark nest, ready to blow your head off."

"The past is a puzzle, like a broken mirror. As you piece it together, you cut yourself, your image keeps shifting. And you change with it. It could destroy you, drive you mad. It could set you free."

"Your past has a way of sneaking up on you. You'll hear broken echoes of it everywhere, like a bad replay. You'll get mad at everyone for reminding you about it, even if it's all in your head."

"If you think nothing can get to you, you're lying to yourself. At best you're temporarily dead. A lightning bolt could re-animate you without a warning."

"The genius of the hole: no matter how long you spend climbing out, you can still fall back down in an instant."

"All this time we got the fable of Sleeping Beauty wrong. The prince didn't kiss her to wake her up. No one who slept for a hundred years is likely to wake up. It was the other way round. He kisses her to wake himself up from the nightmare that has brought him there."

Sorry for the long post, but if anyone says game quotes I go fucking crazy. I love game quotes, especially Max Payne and Metal Gear Solid. I would probably put more funny ones in, but that would take up far too much space.

"all your base are belong to us"

STOP POKING ME!!

raab13:
"all your base are belong to us"

Roses are #FF0000 violets are #0000FF all my base are belong to you

Vidic's speech about books and Al Mualim's speech about illusions when you return to Masyaf in Assassin's Creed.

Crap_haT:

raab13:
"all your base are belong to us"

Roses are #FF0000 violets are #0000FF all my base are belong to you

I'm #00FF00 with envy.

stompy:

mathias53:
Gaz "Wow you guys actually came back for me"
Price "Yeah well your ass had all the C4"

Sorry, but that's Griggs they save (remember, he get separated, and the whole first half of Ultimatum is to find him). Yes, he is the stereotypical black guy, with the C4, LMG and who raps at the end.

Yes I just was too lazy to go back and check, and I new it was the black guy, my friend was WRONG!!

Hey i got dibbs on that quote already

"What can change the nature of a man?" - (Ravel, PST)

I could go on quoting from Planescape Torment all day, but I won't.

As much as I like GLaDOS let's not forget the mother of all insane AI's;

"Look at you, Hacker. A pathetic creature of meat and bone, panting and sweating as you run through my corridors. How can you challenge a perfect, immortal machine?" -(Shodan, SS)

"In my talons, I shape clay, crafting life forms as I please. Around me is a burgeoning empire of steel. From my throne room, lines of power careen into the skies of Earth. My whims will become lightning bolts that devastate the mounds of humanity. Out of the chaos, they will run and whimper, praying for me to end their tedious anarchy. I am drunk with this vision. God: the title suits me well." - (Shodan, SS)

And for something different;

"Jesus, Conrad, tie your fuckin' laces!" - (Riflemen, CoH)

COD4- We're going deep and we're going hard.

"Mind your own business, Fox!" - Falco, Starwing

"RAAUUGH! ROAUFF!" - Random monster agro, Doom
"AAHOUUUUH!" - The two Hell Knights at Knee Deep in Hell, Doom
"It's time to kick ass and chew bubblegum!.. And I'm all outta gum.." - Duke Nukém 3D

"Stop poking me!" - Orc Grunt, Warcraft 2
"-gets transmission in- Stop Poking me!" - Protoss Observer, Starcraft, captured the sound of a Orc Grunt, Warcraft 2.

And the most memorable one..

"Well, don't you look familiar.." - Garland (Chaos), Final Fantasy I (This version line is from Dawn of Souls remake on GBA)

"!"

"The only thing I can assure you of, Arcturus, is that without my help, you'll be the Emperor of your own little eight by eight cell for the rest of your life."

"I don't think so, Admiral. You see, at this point... I'm pretty much the Queen Bitch of the Universe. "

"Uh-oh, doesn't sound good"

"That wasn't supposed to happen"

There is no such thing as innocence, only degrees of guilt.
An open mind is like a fortress with it's gates unbarred and unguarded.
Knowledge is power, hide it well.

All from the librarian in DoW.

x434343:

ratix2:

x434343:
[quote=IanDangerously]
"I'm not joking. And don't call me Shirley."

im only posting this because im anal, and its one of the funniest movies ever made, but that quote actually came from a movie called airplane with leslie nielsen. since then that same line has been used in hundreds of movies, books, commericals, tv shows, games, etc. but great quote none the less.

I know they ripped that off. It's an example of a work referenced in another work. Look, in 30 years, there'll be movies with a line "Are you takin' a piss?" over a radio relay in a completely unrelated movie to war and the creators of said movie will have loved Call of Duty 4.

I know I'm very late to be mentioning this but it's not unrelated. The quote is from the film aeroplane. It is used in the final level of cod4. Setting of said level? An aeroplane! I pissed myself laughing with that one. On a sidenote the "shotgun for close encounters" line is from Aliens. And the first moment in CoD4 that sent shivers down my spine (the part where cappy Price picks you up and says "ON YOUR FEET SOLDIER,WE-ARE-LEAVING!!!!") is from aliens too.

redstar alpha:
"SHOOT!SHOOT! YOU WANKERS!"
cod4 and a line from company of heroes

If you're going to go with CoH, any line said by the Brits is solid gold.

"What?! You're volunteering us again?"

"He's eating my B-B-Brainsssssss"
classical stubbs the zombie

"I'm going to speak to you directly, Dr. Freeman. Yes. I'm talking to you. The so called one free ma-"(gets hit by falling piano)
-Hilarious Gmod Video

"I am a grieving widow" from the milkman level of psychonaughts makes me laugh every time. That and the secret agent who pretends to be a housewife by talking about pies.

From No One Lives Forever, two random thugs that are, essentially, cannon fodder for Cate Archer.

Thug 1: Our studies show that criminals drink three times as much alcohol as law abiding citizens.
Thug 2: So beer turns people into criminals?
Thug 1: A correlation doesn't imply causality. Just because criminals drink a lot of beer doesn't mean that beer causes crime. It's possible that people with criminal tendencies enjoy beer because it helps to soothe their conscience. Or perhaps criminal behavior is caused in part by a genetic predisposition that also, coincidentally, makes criminals like the taste of beer more than the average person. Who knows?
Thug 2: You're very knowledgeable about these things.
Thug 1: Criminal sociology is a hobby of mine. I think it's important to understand not just the individual, psychological roots of one's behavior, but also the social circumstances that foster that behavior. Whether we like it or not, we are shaped by our environment.
Thug 2: Surely you're not suggesting that individuals aren't accountable for their actions.
Thug 1: Oh, no, of course not. Just because we are products of the societies we're born into doesn't absolve us of personal responsibility. Our religions and laws teach us what is right and what is wrong. Frequently, the right choice is the more difficult path to take. It requires sacrifice, self-discipline, patience ... virtues that many of us find somewhat lacking in our natures.
Thug 2: But what if you're born into a hedonistic culture?
Thug 1: Look across history. The reason hedonism is discouraged by most religions and governments is that it weakens a civilization. It breeds sloth, petulance, degeneracy, and selfishness. A divided nation is a fragile nation, waiting to be conquered. Unity is strength. Humans instinctively fashion order out of chaos. It is a natural, probably genetic impulse. Therefore, even an individual born into troubled times has the capacity, and even the duty, to behave in a manner that promotes unity, however difficult it may be.
Thug 2: Then what about us?
Thug 1: I can only speak for myself. I am a product of a broken household, which introduced a general lack of self confidence in me at a very early age. These feelings of inadequacy blossomed into anger as I matured that the rigors of adolescence, with the teasing and abuse and awkwardness we must all endure, only exacerbated. But even though I've identified the source of my problems, I'm still too childish and petty to become a responsible, mature citizen.
Thug 2: Well, admitting you have a problem is the first step, I suppose.
Thug 1: I like to think so.

And from the sequel, No One Lives Forever 2.

Melvin Blitzny: "She wasn't good looking and she smelled like a horse, but she was woman enough for me!"