Bioshock-That shocking twist that im sure everyone remembers so well I dont even have to describe it.

Also Castlevania SOTN-finding out that 'Alucard' The main character is 'Dracula' spelt backwards.

Fallout 3 pissed me off because the game denied it's own logic. It's okay when a game doesn't make sense because it's unrealistic, as long as it has some sort of logic. Fallout 3 seemed hellbent on denying the very rules it created. Examples include: The enclave can make the the most advanced weapons and armor, and have a crazy computer leading them but can't guess or hack a 3 digit passcode. The whole business at the end where you can have mounds of rad-x and rad-away, plus a companion who's very purpose IN THE GAME is to walk through radiation so you don't have to, and you still have to die from rad poisoning.

Worst:

Best:
1.) Tales of Symphonis
2.) Knights of the Old Republic

FFT - EVERYBODY IS EVIL with the exception of Ramza and those who befriend him.

GuerrillaClock:
best - Second Sight

Spoiler: Click to View

I forgot about that, definitely one of my favorites.

Shadow of Destiny had an interesting twist

Silent Hill 2 had a great twist, although it was sort of predictable.

Edit; for good twists I forgot to mention Digital Devil Saga 1 and 2!

The worst is unquestionably Indigo Prophecy. That game was so incredible until about the halfway mark. I'm not using spoiler brackets because everyone should read this if they've considered buying the game so they can realize it's a pile of crap.
Why is all of this interesting stuff happening to our hero? Because of an ancient cliche cult and you're targeted essentially because you're 'the one.' And during action sequences you later begin to fly and shoot lasers from your hands.
It was absolutely terrible.

Good morning blues:
The best for me was Knights of the Old Republic (the revelation regarding your past). I didn't see it coming at all, and yet it didn't feel out of place.

.

Pretty much ^

Uskis:

Isaac Dodgson:
Bioshock has an awesome plot twist...one which I will not go into detail on, as i feel even putting it in spoiler tags would spoiler it somewhat

Yeah. I have to put my vote on that one too. I didn't see it coming, and when the whole thing is revealed I was pretty impressed. Hands down, I didn't see it coming, even after I walked through a room full of spoilers.

I third this, I easially the best plot twist theres ever been in game.

Another good one was Warrior Withins plot twist. I didn't like most of that game, especially when compared to Sands of Time. But, though the atmosphere was emo tastic the story was still very strong.

Also Assassins Creed is the worst plot twist. We all saw it coming, plus the end was just a massive kick in the balls, so much so that I doubt I'll get the next one.

Baten Kaitos had some great twists!

The voice acting wasn't amazing, but it was worth it for the awesome plot.

hmm... since all the obvious ones have been said already - I almost say COD4.... I mean it wasn't exactly a twist, you knew the nuke could go off and your character could out and out die... but you just don't expect it at all

CmdrGoob:
FF8 has the two worst twists, because there's that and there's the whole retarded twist at the end that the real big bad is someone else you never even heard who's thrown in at the last minute.

Holy crap, I completely forgot about that. And I don't know why, because that was the straw that made me drop the game completely. I got right up to the very end and then realized that I had no idea why I was subjecting myself to it.

I gave it another try a few years ago, but I just couldn't get past the terrible combat and the hideous graphics. How people think that game looks better than FFVII I have no idea - Cloud may have only been vaguely human shaped, but at least he wasn't constructed out of a mess of pixels.

JBarracudaL:
The worst is unquestionably Indigo Prophecy. That game was so incredible until about the halfway mark. I'm not using spoiler brackets because everyone should read this if they've considered buying the game so they can realize it's a pile of crap.
Why is all of this interesting stuff happening to our hero? Because of an ancient cliche cult and you're targeted essentially because you're 'the one.' And during action sequences you later begin to fly and shoot lasers from your hands.
It was absolutely terrible.

Ahahahaha, I loved that game until all that stupid Aztec bullshit started - and that's strange, since I'm usually all over anything that uses mythology that I'm unfamiliar with. In this case, however, it was completely out of place, and had no grounding in the really awesome intrigue and creepy paranormal shit that was going down beforehand. A good twist is a twist where you can see the hints beforehand, but you don't. There were no hints here - you were just smacked with something that had no relation to the game you'd been playing.

It's not that Indigo Prophecy/Fahrenheit had the Aztec bullshit that was the problem. It was that it had both Aztec bullshit and Matrix bullshit going at the same time that was the ultimate turn-off.

Half-Life 2: Episode 2 had the best, most intense cliffhanger in the world. For you crazy people who don't know what it is, I'll have to put up a spoiler.

In fallout 3 when you were in the other world as a kid and it turns out your dad was the dog. Talkin about a screw fest

I loved the twist in bioshock where you learn that Atlas is actualy Frank Fontain, and that you were being controlled bye him.

The World Ends With You had some of the best plot twists I've encountered:

Mm ... as for worst... yeah, I'll throw my hat in for the random FFIX end-villain, which also happened in Legend of Dragoon, and FF8, where HEY SURPRISE what you thought you were fighting against wasn't it at all but really something from behind the scenes but .. blagh.

Link's Awakening.

No, Link. You did not just save an entire island of innocents from monsters. It was all just a dream that you woke from. So, in essence, you actually killed them.

Good job breakin' it, Hero.

Pretty much all of the Raiden section of MGS2 was just one huge chain of "wait, what?" scenarios.
Although I doubt Plisken turning out to be snake can even be called a plot-twist, more like a sarcastic "oh really?"
As I hadn't played MGS1 before though I really had no idea what was going to happen next most of the time...

Braid

Isaac Dodgson:
Bioshock has an awesome plot twist...one which I will not go into detail on, as i feel even putting it in spoiler tags would spoiler it somewhat

Oh wow, that one is awesome indeed.

No one gonna say Bioshock? Would ya kindly (Fill in blank) That was great, I thought so anyway.

*EDIT* I was typing this when someone also said Bioshock. Funny...

I dunno, I think hte least obvious betrail ending was from Crackdown. Honestly didn't see that one coming

Well, KOTOR has been said, so...

People have said FF6 had a good plot twist.

WHERE IS THERE A TWIST IN FF6???

scnj:
Braid

Spoiler: Click to View

I know, that blew my mind.

Honorable mentions the usual suspects, KotOR, Silent Hill 2 and Bioshock.

Metroid ladies and gents.

"Sweet, I beat the game... HOLY CRAP SAMUS IS A GIRL!!!!!!!!!!!!!!!!!!!!!!"

I can't believe how many people liked the bloody thing in KotoR. I almost gave up and quit the game when that happened because it was just so bloody ridiculous.

System Shock 2.

KOTOR's twist was okay, but it was a bit too easily guessable.

JBarracudaL:

The worst is unquestionably Indigo Prophecy. That game was so incredible until about the halfway mark. I'm not using spoiler brackets because everyone should read this if they've considered buying the game so they can realize it's a pile of crap.
Why is all of this interesting stuff happening to our hero? Because of an ancient cliche cult and you're targeted essentially because you're 'the one.' And during action sequences you later begin to fly and shoot lasers from your hands.
It was absolutely terrible.

It might be a strange plottwist, but that doesn't make the game a bad game. Most people here will agree that the game itself was refreshingly new and that the game is really good.

Scumsberg:
When Fallout 3 forced you to kill yourself (or Lyons) despite giving you three radiation immune companions (Fawkes, Charon and the robot). Fawkes actually told me suicide was my destiny and he wouldn't interfere with it - despite that he could have prevented anyone from dying with no risk to himself.

What the fuck, Bethesda?

Indeed. What the fuck. It's your destiny to die?

OH! OH OH OH!
Not plot related but still a twist.

FAWKES USED TO BE A GIRL!

Scumsberg:
When Fallout 3 forced you to kill yourself (or Lyons) despite giving you three radiation immune companions (Fawkes, Charon and the robot). Fawkes actually told me suicide was my destiny and he wouldn't interfere with it - despite that he could have prevented anyone from dying with no risk to himself.

What the fuck, Bethesda?

Oh, man I was pissed.
Friggin', Like, wtf!
you hit the nail right on it's twisted head.

popdafoo:
Half-Life 2: Episode 2 had the best, most intense cliffhanger in the world. For you crazy people who don't know what it is, I'll have to put up a spoiler.

Spoiler: Click to View

I hated that. It's like Valve decided near release that not enough happened in Episode 2 and threw something in at the end.

Silver:
I can't believe how many people liked the bloody thing in KotoR. I almost gave up and quit the game when that happened because it was just so bloody ridiculous.

It's Star Wars! Like the overdone accents.

Scumsberg:
Fawkes actually told me suicide was my destiny and he wouldn't interfere with it - despite that he could have prevented anyone from dying with no risk to himself.

Whoa, really? That's a pretty ballsy move considering that you're holding a little tube of something that will KILL EVERY GODDAMN SUPERMUTANT.

-- Alex

In Fallot 3; traveling the waistland with a Super Mutant companion (Fawks). I mean even he's surprised (as he often comments about it) that "it's amazing how people trust you enough to not attack me" or something like that. It even sometimes surprises me to turn around and see that big angry looking creature following me, and then realizing that he's on my side, with that kick ass gatling laser; and this guy is virtually invincible cause a car blew up right next to him and he wasn't even limping afterwards.

Jade Empire had a very dramatic plot twist I did not see coming when Master Li betrays you.