Depending on your actions in Infamous 2, you will forge a better friendship with one of two female companions.
The first Infamous had a karma system and your choices in the missions changed what powers were available to the hero Cole. In the sequel, Sucker Punch is making the morality system a little more personal by creating two characters: Kuo and Nix. Nix is a native of the Louisiana city where the game is set (a New Orleans ripoff called New Marais) and she hates the villain Bertrand with a passion that blinds her to the consequences of her actions. Kuo is an NSA agent. From those descriptions it's pretty clear that Nix is the "bad" NPC while Kuo is "good." By choosing different dialogue options and following the lead of one of these characters will affect how you play Infamous 2.
"There will be multiple crossroads where Cole will decide to follow Kuo's lead or give into Nix's temptations. Your choices will directly affect the gameplay by permanently remaining in the world," read the announcement on the PlayStation blog. "Whatever path you choose, remember that in inFAMOUS 2 you can always change your mind. It's never too late to look for redemption ... or to say "to hell with it" and become selfish."
That last bit alone will be a big improvement over the first game as it became frustrating if you wanted to change which way your morality was leaning. I'm glad that Sucker Punch listened to fans complaints about that portion of the game and created a new system that appears to solve the problem.
By the way, judging by those screenshots, the game looks pretty damn good. I saw it at E3 and the team has almost had 10 months to perfect the systems and graphics to take the best advantage of the PS3 hardware.
There's still no word on an official release date other than 2011, but the excitement is building.
Source: PlayStation Blog